This workshop is designed for beginners and relatively experienced individuals dealing with clinical pharmacology related data analytics in their day to day work. Individuals interested in performing Non-compartmental analysis on their clinical data or use basic or advanced non-linear mixed effects models to capture the variability in drug pharmacokinetics or response and the contribution of covariate effects and/or simulate new dosing scenarios or clinical trials will find this workshop interesting.
Workshop Agenda (Tentative)
December 5, 2022
• 08:30 - 08:50 - Setting up the workspace
• 08:50 - 09:15 - JuliaHub - Instances and File Explorer
• 09:15 - 10:00 - NCA
• 10:00 - 10:15 - Coffee break
• 10:15 - 10:45 - Bioequivalence
• 10:45 - 12:30 - Population Pharmacokinetic modeling Part 1 - Overview of Pumas and Pumas Workflow
• 12:30 - 13:30 - Lunch break
• 13:30 - 14:30 - Population Pharmacokinetic modeling Part 2 - Iterative Model Building
• 14:30 - 14:45 - Coffee break
• 14:45 - 15:30 - Model-based Optimal Design
• 15:30 – 17:00 – Hands-on project
December 6, 2022
• 08:30 - 10:00 - Model Diagnostics Part 1 - Plotting
• 10:00 - 10:15 - Coffee break
• 10:15 - 11:15 - Model Diagnostics Part 2 - Model qualification
• 11:15 - 12:30 - Sequential PKPD
• 12:30 - 13:30 - Lunch break
• 13:30 - 14:30 - Data Wrangling
• 14:30 - 14:45 - Coffee break
• 14:45 - 15:30 - Sneak peek into DeepPumas, AI-based Pumas
• 15:30 - 17:00 - Hands-on project and general discussion